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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KSR2
All Species:
13.33
Human Site:
S243
Identified Species:
29.33
UniProt:
Q6VAB6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VAB6
NP_775869.3
950
107632
S243
C
P
P
P
P
L
E
S
G
H
R
S
L
P
P
Chimpanzee
Pan troglodytes
XP_001145739
986
111275
S219
C
P
P
P
P
L
E
S
G
H
R
S
L
P
P
Rhesus Macaque
Macaca mulatta
XP_001083311
805
90894
S167
G
F
T
A
L
H
R
S
K
S
H
E
F
Q
L
Dog
Lupus familis
XP_853953
898
99758
D237
V
S
A
L
P
T
S
D
S
L
P
P
G
P
C
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVC0
959
108554
S244
P
P
P
P
P
L
E
S
G
H
R
S
L
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514916
259
29171
Chicken
Gallus gallus
Q04982
806
89347
V168
L
P
N
K
Q
R
T
V
V
P
A
R
C
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137513
942
106704
T241
H
F
P
S
P
L
E
T
G
H
H
S
L
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11346
782
88616
Q144
E
Q
P
H
Y
Q
N
Q
T
Q
I
L
Q
Q
Q
Honey Bee
Apis mellifera
XP_393005
895
100160
S217
S
S
I
T
S
L
S
S
T
S
P
P
S
T
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
A183
A
L
R
L
S
S
E
A
T
C
A
D
D
P
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
84.3
51
N.A.
95.5
N.A.
N.A.
25.1
24.3
N.A.
82.3
N.A.
24.9
36.4
N.A.
N.A.
Protein Similarity:
100
92.1
84.5
64.6
N.A.
97
N.A.
N.A.
26.3
40.2
N.A.
90.1
N.A.
40.9
53.5
N.A.
N.A.
P-Site Identity:
100
100
6.6
13.3
N.A.
93.3
N.A.
N.A.
0
6.6
N.A.
66.6
N.A.
6.6
20
N.A.
N.A.
P-Site Similarity:
100
100
6.6
13.3
N.A.
93.3
N.A.
N.A.
0
6.6
N.A.
73.3
N.A.
6.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
10
0
0
19
0
0
0
0
% A
% Cys:
19
0
0
0
0
0
0
0
0
10
0
0
10
0
10
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
10
10
0
0
% D
% Glu:
10
0
0
0
0
0
46
0
0
0
0
10
0
0
0
% E
% Phe:
0
19
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
37
0
0
0
10
10
0
% G
% His:
10
0
0
10
0
10
0
0
0
37
19
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
10
10
0
19
10
46
0
0
0
10
0
10
37
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
10
37
46
28
46
0
0
0
0
10
19
19
0
55
46
% P
% Gln:
0
10
0
0
10
10
0
10
0
10
0
0
10
19
10
% Q
% Arg:
0
0
10
0
0
10
10
0
0
0
28
10
0
0
0
% R
% Ser:
10
19
0
10
19
10
19
46
10
19
0
37
10
0
0
% S
% Thr:
0
0
10
10
0
10
10
10
28
0
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _